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Most traditional metabolism supplements rely on caffeine, green tea extract, or capsaicin, which provide short-term thermogenic effects rather than sustained appetite regulation

The move is expected to save the state an estimated $240 million

Initially developed for type 2 diabetes, GLP-1RAs have demonstrated robust weight loss in randomized controlled trials and real-world settings, leading to their repositioning as cornerstone obesity treatments ( Human metabolic studies consistently show that reductions in energy intake account for most of the weight loss observed during GLP-1RA therapy, whereas increases in resting energy expenditure are modest or absent ( Beyond total weight loss, the quality of weight loss has become an increasingly important clinical concern

In this regard, the translational relevance of this preclinical study was demonstrated in patients with obesity by correlation of: (1) circulating FGF21 levels 4 weeks after mRYGB with the initial fat mass and one-year body weight reduction, (2) circulating FFAs with 4 week-body weight loss in mRYGB patients and (3) circulating adiponectin and OXM with weight loss